Cervical cancer resources
A range of cervical cancer resources are presented in this section.
Key facts | Reports | Briefings | Posters | Presentations | Evidence | Guidance for health professionals | Interventions| Site Specific Clinical Reference Group
Key facts
Cancer Research UK CancerStats
http://info.cancerresearchuk.org/cancerstats/types/cervix/
Statistics and information about cervical cancer risk factors and screening, aimed at health professionals, provided by Cancer Research UK.
GLOBOCAN 2012 and other international cancer databases
http://globocan.iarc.fr/Default.aspx
The GLOBOCAN project provides contemporary estimates of the incidence of, mortality and prevalence from major types of cancer, at a national level, for 184 countries of the world. Current estimates are for 2012.
The website also provides links to other international cancer databases and resources including Cancer Incidence in 5 Continents - access to detailed information on the incidence of cancer recorded by regional or national cancer registries worldwide and the European Cancer Observatory (ECO) - a one-stop web-based tool for accessing, analysing and downloading European cancer data.
Reports
This report presents analyses of the Patient Reported Outcomes Measures (PROM) data, offering a descriptive summary of responses to a pilot of patient reported outcome measures for gynaecological cancers and provides a much needed insight into the health and wellbeing of women living with and beyond cervical cancer.
This report results from a collaboration between the NHS Cervical Screening Programme and Trent Cancer Registry as the National Cancer Intelligence Network’s lead registry for gynaecological Cancers. It shows the latest time trends, trends by age and deprivation, and regional variations in incidence, mortality and survival for invasive cervical cancer in England. There is also a separate section on these cases stratified according to their main morphological groups. It should be of interest to all those involved in the commissioning and delivery of services to prevent and treat cervical cancer. A Powerpoint slideset presenting analyses from the report is also available.
This report was produced by Trent Cancer Registry, as NCIN lead cancer registry for gynaecological cancers, in collaboration with the NHS Cervical Cancer Screening Programme. It highlights interesting and important findings about time trends, trends by age and depriviation, and regional variations in incidence, mortality and survival for invasive cervical cancer in England.
This initial report on major surgical resections in England presents the percentage of NHS treated cancer patients who received a major resection as part of their treatment. The report contains results for thirteen cancer sites, including cervix, ovary and uterus, and covers patients diagnosed during 2004-2006 who were followed up to 2007. Percentages are presented by sex, age, deprivation quintile and cancer network, with funnel plots depicting both percentages and indirectly age-standardised ratios by cancer network. Cancer networks have been assigned by the residence of patients at time of diagnosis. These data provide a basis to instigate further exploration of major surgical resections for cancer patients and to encourage improved recording and sharing of data to allow further analyses to be produced.
Cancer Statistics Registrations, England (Series MB1), ONS
http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-27454
Numbers and rates of newly diagnosed cases of cancer by site, sex and age, including invasive and non-invasive carcinoma of the cervix released by the Office for National Statistics (ONS).
Cancer Incidence and Mortality in the UK
http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-21518
Incidence and mortality statistics for 21 common cancers by sex, including cervical, released by ONS.
Cancer Survival Rates in England
http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-21521
One and five-year survival statistics for 21 common cancers by sex and age, including cervical, released ONS.
NHS Information Centre Indicator Portal
https://indicators.ic.nhs.uk/webview/
The NHS Information Centre indicator portal brings together a number of health and social care indicators. These include the Compendium of Population Health Indicators, which has incidence, mortality and survival data for cervical cancer and includes cervical screening coverage data.
National Cancer Patient Experience Survey
http://www.quality-health.co.uk/surveys/national-cancer-patient-experience-survey
Information about the National Cancer Patient Experience Survey Programme and access to the survey results for each Hospital Trust.
Since April 2007, the regional Quality Assurance Reference Centres (QARCs) in England have adopted a standardised protocol for capturing screening data on all cases of cervical cancer. The data are aggregated in a national database for the purpose of audit, with the aim of monitoring and improving the service.
Annual national reports detailing the data collected as part of this audit are published as feedback for the many individuals who make this audit possible.
This year's annual review reflects on the roll-out of HPV triage, and explores the impact of wider changes to the NHS on the cervical screening programme. Feature articles explore the continuing impact of Jade Goody’s untimely death on cervical screening uptake, and investigate a groundbreaking project to improve screening uptake amongst the black and minority ethnic community in Dudley
NHS Cervical Screening 2011 Review
http://www.cancerscreening.nhs.uk/cervical/publications/cervical-annual-review-2011.pdf
This report features the development of the Quality Assurance aspects of HPV testing, which is being introduced as a second line screening test into the NHS Cervical Screening Programme. It also looks at research analysing the relationship between falling uptake of cervical screening in hard-to-reach groups and cervical cancer incidence, and a study which will evaluate interventions aimed at increasing participation by women when they receive their first screening invitation.
Briefings
Trachelectomy is a relatively new interventional procedure for women diagnosed with cervical cancer. It is usually carried out for the treatment of stage IIA or lower disease in women who would prefer to retain fertility. The briefing aims to assess the use of HES data to identify this procedure and measure variation over time and across regions of England. On average, around 60 women per year received the intervention between 2006 and 2013. There was a peak of 76 cases in 2013, accounting for 6.4% of cervical cancers diagnosed among women aged 45 and under at stage IIA or less. There is some regional variation in the proportion of these women receiving the intervention from 2.0% in Yorkshire and the Humber to 9.0% in London. This variation may be due to differences in clinical management or the recording of the procedure in the HES data. However, it is also likely to be related to the requirement of fertility sparing treatment into later age among the less deprived populations of the southern regions compared to northern regions.
There has been an increase in the incidence of cervical cancer in women aged under 35 since the late 1990’s. Over this time there has also been a steady fall in the coverage of screening in women of this age group; however in the last two years coverage has increased. It is important that this trend continues, so that the number of women who develop cervical cancer may be reduced. Data briefing prepared by Trent Cancer Registry and NHS Cancer Screening Programmes.
Posters
2013
How much could primary HPV testing reduce cervical cancer incidence and morbidity in England?
Cervical cancer - presentation, diagnosis and treatment, N.Ireland, 2010
Criteria to identify radical trachelectomies using the NCDR and HES data
Routes to diagnosis for gynaecological cancer patients
Earlier
Improving in-situ cervical cancer registry data (2009)
National cervical cancer profile report (2010)
Presentations
This slide set has been produced to accompany the Profile of Cervical Cancer in England, 2012 and presents charts taken from the report. Analyses include the latest time trends, trends by age and deprivation, regional variations in incidence, mortality and survival and cases stratified by the main morphological groups.
Evidence
Links to peer-reviewed papers and journals dedicated to cervical cancer and online, searchable libraries, providing details of relevant research and publications in journals and elsewhere.
British Journal of Obstetrics and Gynaecology
http://www.bjog.org/view/0/index.html
The official journal of the Royal College of Obstetricians and Gynaecologists RCOG.
The Cochrane Collaboration
http://www.cochrane.org/index.htm
The Cochrane Collaboration makes information available regarding the effects of healthcare and produces and disseminates systematic reviews of healthcare interventions.
European Cervical Cancer Association
http://www.ecca.info/en/
The European Cervical Cancer Association aims to raise awareness of cervical cancer and its prevention among members of the general public, healthcare professionals and public health decision-makers in Europe.
Gynaecological Cancer Centre - Barts and The London
http://corporatebarts.demo2.steellondon.com/our-services/gynaecological-cancer-centre/research
Barts and The London Gynaecological Cancer Centre conduct research projects into gynaecological cancer with the aim of improving current cancer treatments and patients’ survival. Research is conducted by team members from the Gynaecological Cancer Centre and colleagues from the Centres for Translational Oncology and Molecular Oncology within the Institute of Cancer at Barts and the London, Queen Mary School of Medicine and Dentistry.
Gynaecological Cancer Centre - Pan Birmingham
http://www.swbh.nhs.uk/services/d-g/gynaecology-cancer/research
The Pan Birmingham Gynaecological Cancer Centre is the hub of the pan-Birmingham gynaecological cancer network which provides tertiary level care for 5 cancer units. The centre is involved in prioritized clinical trials and translational research activity in oncology and has close links with the School of Cancer Sciences at the University of Birmingham.
Gynaecological Cancer Centre - West London
http://www1.imperial.ac.uk/surgeryandcancer/divisionofcancer/reproductivebiology/obsgyn/translational_research/gynaecological_oncology
Patients from 15 hospitals are referred to the West London Gynaecological Cancer Centre for multidisciplinary treatment for gynaecological malignancy. Patient management is underpinned by clinical and translational research.
Gynaecological Cancer Research Centre - University College London
http://www.instituteforwomenshealth.ucl.ac.uk/academic_research/gynaecologicalcancer/gcrc
The Gynaecological Cancer Research Centre is based at the Institute for Women’s Health at UCL. The group oversees and coordinates large multi-centre trials, with the overall aim of reducing mortality and morbidity of women with gynaecological malignancies through screening, early diagnosis and risk prediction.
Gynaecological Oncology Group - University of Manchester
http://www.medicine.manchester.ac.uk/cancerstudies/research/gynaecological/
The Gynaecological Oncology Group is based within the Academic Unit of Obstetrics and Gynaecology Group at St Mary's Hospital, Manchester. The Group hosts programmes of biomedical science as well as clinical trials and has been established as a leading centre of human papillomavirus (HPV) research both nationally and internationally.
Gynaecologic Oncology
http://www.sciencedirect.com/science/journal/00908258
The official journal of the Society of Gynaecologic Oncology (SGO).
Gynaecology Unit - The Royal Marsden
http://www.royalmarsden.nhs.uk/consultants-teams-wards/clinical-units/pages/gynaecology-unit.aspx
The Gynaecology Unit at the Royal Marsden provides multidisciplinary team management of gynaecological cancers for the South West London Cancer Network. The Unit is also involved in a varied programme of clinical research projects.
International Journal of Gynecological Cancer (IJGC)
http://journals.lww.com/ijgc/pages/default.aspx
The official journal of the International Gynecologic Cancer Society (IGCS) and the European Society of Gynaecological Oncology (ESGO).
National Cancer Peer Review Programme – CQuINS
http://www.cquins.nhs.uk/index.php?menu=resources
Information about National Cancer Peer Review (NCPR), a national quality assurance programme for NHS cancer services and access to the guidelines for gynaecological cancer.
NHS Evidence - cervical cancer
https://www.evidence.nhs.uk/topic/cervical-cancer
Searchable database providing evidence-based information on many health-related topics, including cervical cancer, aimed at professionals across the NHS, public health and social care sectors.
National Cancer Research Institute (NCRI)
http://www.ncri.org.uk
The National Cancer Research Institute (NCRI) is a UK-wide partnership between the government, charity and industry which promotes co-operation in cancer research among the 22 member organisations for the benefit of patients, the public and the scientific community.
National Institute for Health Research Cancer Research Network
http://ncrndev.org.uk
The National Institute for Health Research Cancer Research Network (formerly the National Cancer Research Network) was established by the Department of Health in April 2001 to provide the NHS with an infrastructure to support prospective trials of cancer treatments and other well-designed studies, and to integrate and support research undertaken by cancer charities. Its aim is to improve the speed, quality and integration of research, ultimately resulting in improved patient care. The website also includes details of the Local Cancer Research Networks across England.
Peer-reviewed paper on gynaecological symptoms and potential for earlier cervical cancer diagnosis
Stapley S and Hamilton W, Gynaecological symptoms reported to primary care by women aged 15–29 years: a historical cohort study using electronic medical records, examining the potential for earlier diagnosis of cervical cancer, Family Practice (2011) doi: 10.1093/fampra/cmr033 (First published online: June 1, 2011)
PubMed
http://www.ncbi.nlm.nih.gov/pubmed
Database of citations from MEDLINE and life sciences journals, provided by the U.S. National Library of Medicine and the U.S. National Institutes of Health.
World Cancer Research Fund International
http://www.wcrf.org/cancer_statistics/data_specific_cancers/index.php
The World Cancer Research Fund International (WCRF) website has information on the most common cancers affecting men and women worldwide and includes data on cervical, ovarian and uterine cancer.
Guidance for health professionals
The British Gynaecological Cancer Society (BGCS)
http://www.bgcs.org.uk
The BGCS works to improve the care provided to patients with gynaecological cancers. The BGCS website includes information for both patients and health professionals.
British Society for Colposcopy and Cervical Pathology (BSCCP) guidelines
http://www.bsccp.org.uk/index.asp?PageID=20
BSCCP current national guidelines, including the current national guidelines for colposcopy (Colposcopy and Programme Management. Guidelines for the NHS cervical screening programme. NHSCSP publication no. 20, May 2010).
Cervical Screening Wales
http://www.screeningservices.org.uk/csw/pub/index.asp
Information about the NHS Cervical Screening Programme for Wales.
Clinical practice guidelines for the assessment of young women aged 20-24 with abnormal vaginal bleeding
http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_113478
Guidance for primary care on the management of young women who present with gynaecological symptoms, published by the Department of Health in March 2010. This was produced by a multi-disciplinary group, including professionals, patients and the voluntary sector, following a review of the cervical screening age by the Advisory Committee on Cervical Screening (ACCS) in May 2009.
European Society of Gynaecological Oncology (ESGO)
http://www.esgo.org
The ESGO is the principal European society contributing to the study, prevention and treatment of gynecological cancer.
International Gynecologic Cancer Society (IGCS)
http://www.igcs.org/
The IGCS is a not for profit independent organisation contributing to the prevention, treatment and study of gynecologic cancer, as well as improvement in the quality of life among women affected by gynecologic cancer throughout the world.
NHS Cervical Screening Programme
http://www.cancerscreening.nhs.uk/cervical
Information about the NHS Cervical Screening Programme for England.
NICE guidance on cervical cancer
http://www.nice.org.uk/guidance/index.jsp?action=byTopic&o=7170&ht=7165
Guidance released by the National Institute for Health and Clinical Excellence relating to the diagnosis and treatment of cervical cancer.
NI Cervical Screening Programme
http://www.cancerscreening.hscni.net/cervical/toc.html
Information about the Northern Ireland Cervical Screening Programme.
Royal College of Obstetricians and Gynaecologists (RCOG)
http://www.rcog.org.uk
The RCOG works to advance the science and practice of obstetrics and gynaecology, through education, training and the publication of clinical guidelines and reports on aspects of the specialty and service provision.
Scottish Cervical Screening Programme
http://www.nsd.scot.nhs.uk/services/screening/cervicalscreening/index.html
Information about the NHS Cervical Screening Programme for Scotland.
Scottish Intercollegiate Guidelines Network (SIGN)
http://www.sign.ac.uk/guidelines/fulltext/99/index.html
SIGN guidelines on the management of cervical cancer.
Society of Gynaecologic Oncology (SGO)
http://www.sgo.org
The SGO works to promote the highest quality of comprehensive clinical care through education and research in the prevention and treatment of gynaecologic cancers
Interventions
Information about an event held in Guernsey to raise awareness of cervical and other gynaecological cancers.
Site Specific Clinical Reference Group
Details of the meetings and membership of the Gynaecological Site Specific Clinical Reference Group.