10-Year survival by stage for the East of England

The National Cancer Registration and Analysis Service (NCRAS) in partnership with Cancer Research UK (CRUK) have produced estimates for 10-year survival by stage at diagnosis for patients diagnosed between 2007 and 2017 for eight cancers (breast, colorectal, kidney, lung, melanoma, ovary, prostate, uterus). This analysis has key differences from the officially produced cancer survival statistics here:

  • This analysis used data from the former East of England cancer registry which has good historic stage at diagnosis data
  • This analysis produced non-age standardised survival estimates

Key points

  • 5-year net survival estimates by stage at diagnosis were calculated and compared between patients diagnosed in a geographical area with good historic stage completeness (the East of England) and England overall; using the complete approach of producing net survival estimates. Estimates for patients diagnosed in the East of England were largely similar to patients in England overall, suggesting the East of England data were representative enough to explore further.

  • 10-year net survival estimates by stage at diagnosis were subsequently calculated for the East of England using the period approach to more accurately reflect the survival experience for those more recently diagnosed.

  • Non age-standardised results are presented because small numbers in age/stage/site combinations make some 10-year age-standardised estimates unfeasible. Estimates were also produced by sex (where appropriate) and age (under and over 65 years).

  • 10-year net survival estimates by stage for breast, colorectal, lung, prostate, kidney, melanoma, ovarian and uterine cancers were generally lower than 5-year net survival, though there was notable variation by site and stage.

  • Melanoma, breast and prostate cancer survival estimates for stage 1 remained high for all time periods, whereas 10-year survival estimates for kidney and lung cancer are lower than 1- and 5-year survival estimates at each stage of diagnosis.

  • The relative difference between 5- and 10-year survival estimates generally increased by later stage at diagnosis

  • Differences between 10-year survival by stage highlight the need for continued efforts to achieve diagnosis at earlier stages

The full technical report with detailed methodology and results can be found here